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Cedro

The CEDRO Group is responsible for the management and operation of the CEDRO beamline of the synchrotron light source Sirius, at the Brazilian Synchrotron Light Laboratory (LNLS).

The CEDRO beamline will be dedicated to the Electronic Circular Dichroism (CD) technique. This technique allows analyzing the secondary structure of proteins and protein-drug complexes, identifying the disordered regions of these proteins, as well as analyzing the interactions of proteins with small molecules, which will contribute to the development of drugs. In addition, the CEDRO beamline will allow the measurements to be carried out under simulated physiological conditions, mimicking the biological environment.

Cedro Beamline

CeDRO (Circular DichROism Beamline) is a beamline dedicated to Circular Dichroism (CD) spectroscopy in the ultraviolet region. This spectroscopy is applied to the structural analysis of chiral molecules, including biomolecules such as proteins, nucleic acids, and carbohydrates. Proteins are extensively studied by CD to quantify their secondary structure content and to analyze folding, stability and interactions in solution.

Coordination

Juliana S. Yoneda
Leader Researcher
+55 19 3512 1045
juliana.yoneda@lnls.br